Hematological Parameters and Inflammatory Markers in Children with Multisystem Inflammatory Syndrome

Abstract
 Objective:
 Multisystem inflammatory syndrome in children (MIS-C), is a newly recognised life-threatening complication of coronavirus disease 2019 (COVID-19). Early determination clinical severity the important for early decision treatment regimens. The aim this study to investigate classification value number hematological parameters, markers and biochemical tests patients with MIS-C during acute stage after anti-inflammatory treatment.
 Material Methods: 
 In retrospective case-controlled study, 64 95 healthy age gender matched were included. Patients divided into three groups; mild, moderate, severe. Results: Mean platelet volume (MPV), MPV lymphocyte ratio (MPVLR), D-dimer, ferritin, interleukin 6 (IL-6) levels significantly higher, while albumin lower severe group compared all other groups on admission. Neutrophil-to-lymphocyte (NLR) derived (d) NLR (d-NLR) higher moderate mild group. pre-treatment period had MPV, distribution width (PDW) values they white blood cell, lymphocyte, monocyte, haemoglobin, mean corpuscular (MCV), red cell (RDW), plateletcrit post-treatment Lymphocyte, platelets, haemoglobin control Acute phase reactants, NLR, NMR, PLR, d-NLR, MPVLR systemic index admission group.
 Conclusion: Specific routine laboratory test results may be useful determining MIS-C, possibly predict prognosis allow initiation appropriate treatment.